Raising Blood Pressure

Progress in prevention: raising the bar to lower blood pressure: key steps to improve blood pressure control rates.

Hypertension (HTN) affects more than 73 million Americans and increases the risk for myocardial infarction, heart failure, stroke, and kidney disease. The relationship between blood pressure (BP) and risk of cardiovascular disease (CVD) events is continuous, consistent, and independent of other risk factors. For individuals aged 40 to 70 years, each increment of 20 mm Hg in systolic BP or 10 mm...

A large blood pressure-raising effect of nitric oxide synthase inhibition in humans.

In experimental animals, systemic administration of nitric oxide synthase (NOS) inhibitors causes large increases in blood pressure that are in part sympathetically mediated. The aim of this study was to determine the extent to which these conclusions can be extrapolated to humans. In healthy normotensive humans, we measured blood pressure in response to two NOS inhibitors, NG-monomethyl-L-argi...

Mechanism of the blood pressure--raising effect of cocaine in humans.

BACKGROUND Although the sympathomimetic actions and cardiovascular complications of cocaine are ascribed to inhibition of norepinephrine (NE) reuptake, this hypothesis has not been tested in humans. We asked (a) whether cocaine can inhibit NE reuptake in the human peripheral circulation and (b) whether the NE-mediated peripheral vasoconstriction is the main mechanism mediating blood pressure-ra...

Comparison of Various Blood Pressure Measurement Techniques with Standard Office Based Blood Pressure Mesurement

Introduction: In order to control Hypertension, it is necessary to understand the methods of blood pressure measurement. Recent guidelines emphasize on employing appropriate blood pressure measurement techniques and white coat hypertension. Definition and methods of blood pressure measurement have changed in the American guideline based on SPRINT trial (Systolic Blood Pressure Intervention Tria...

Blood and Blood-Pressure